Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0493Probable metal chelatase. (2076 aa)    
Predicted Functional Partners:
MMP0491
MotA/TolQ/ExbB proton channel.
 
  
 0.958
cbiA-2
Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA.
 
 
 0.953
cbiA
Cobyrinic acid a,c-diamide synthase.
 
 
 0.948
cbiE
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.938
cbiC
Precorrin-8X methylmutase CbiC/CobH.
 
  
 0.876
MMP0699
C-5 cytosine-specific DNA methylase:Multi antimicrobial extrusion (MatE) protein.
  
  
 0.804
MMP0833
Conserved hypothetical protein.
 
  
 0.793
MMP0492
Conserved hypothetical protein.
  
    0.761
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.756
MMP0490
Conserved hypothetical protein.
  
    0.749
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (28%) [HD]