Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0543Conserved hypothetical protein. (171 aa)    
Predicted Functional Partners:
MMP0544
MoaA/nifB/pqqE family.
  
    0.981
MMP0542
Hypothetical protein.
  
    0.950
mptG
Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
    0.898
MMP1204
Metallopeptidase family M24:Xaa-Pro dipeptidase/Xaa-Pro aminopeptidase.
       0.791
MMP0545
Molybdenum cofactor biosynthesis protein:MoeA N-terminal region, domain I and II:MoeA C-terminal, domain IV.
  
    0.691
MMP0546
Protein of unknown function DUF51.
  
    0.599
MMP1677
4-hydroxybenzoate octaprenyl transferase related protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.580
serB
Phosphoserine phosphatase; Citation: Wang W, Kim R, Jancarik J, Yokota H, Kim SH. (2001) Structure (Camb) 9:65-71.
       0.498
MMP1016
Conserved Hypothetical protein with 4 CBS domains.
   
  
 0.481
MMP0177
Conserved hypothetical archaeal protein.
   
    0.452
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (20%) [HD]