Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP0581Conserved hypothetical protein. (260 aa)    
Predicted Functional Partners:
mptE
Conserved hypothetical archaeal protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
    
  0.956
MMP0644
Cation efflux protein.
  
    0.833
act
Radical-activating enzyme.
  
    0.620
MMP0851
Conserved hypothetical protein.
 
     0.591
MMP0450
Ferredoxin.
 
  
 0.589
MMP0449
Ferredoxin.
 
  
 0.582
MMP0582
AzlC related protein.
       0.546
MMP0583
Conserved hypothetical protein.
       0.518
MMP0451
Conserved hypothetical protein.
 
    0.489
MMP0619
Putative DNA binding protein; Belongs to the UPF0251 family.
 
     0.457
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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