Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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MMP0586Uncharacterized endonuclease III related protein; Citation: Nucleic Acids Res. (2001) 29: 604-613, Nature (2000) 403: 859-866. (232 aa)    
Predicted Functional Partners:
napA
Na+/H+ exchanger.
  
    0.786
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
      0.711
MMP0703
Conserved hypothetical protein.
  
    0.650
MMP0055
Conserved hypothetical Archael protein.
       0.643
MMP0084
Conserved hypothetical protein.
       0.643
bioB-2
TonB-dependent receptor protein:Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
   
    0.620
MMP1550
NADP oxidoreductase, coenzyme F420-dependent.
       0.619
prsA
Phosphoribosyltransferase:Purine/pyrimidine phosphoribosyl transferase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
       0.618
MMP0005
Hypothetical protein.
   
    0.604
dph5
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
  
    0.545
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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