STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atwAMethyl coenzyme M reductase, component A2; Citation: J. Bact. 1993 175: 3196-3203. (531 aa)    
Predicted Functional Partners:
MMP0619
Putative DNA binding protein; Belongs to the UPF0251 family.
  
    0.995
mcrC
Methyl coenzyme M reductase I, protein C; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
    
 0.976
MMP0618
Conserved hypothetical protein; To M.jannaschii MJ1244 and MJ1245 and M.thermoautotrophicum MTH1110.
  
    0.973
mcrD
Methyl-coenzyme M reductase I, protein D; Citation: J. Bacteriol. 1994; 176: 6384-6391. Eur. J. Biochem. 1990; 194: 871-877.
    
 0.971
MMP0107
Hypothetical protein.
  
 
 0.938
MMP0886
Cobalt transport system permease related protein.
  
 
 0.938
cbiQ
Cobalt transport protein Q.
  
 
 0.938
mcrA
Methyl-coenzyme M reductase I, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
    
 0.920
MMP1630
ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase.
  
 
 
0.917
mtbA
Uroporphyrinogen decarboxylase (URO-D).
  
 
 0.909
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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