| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP0642 | MMP0643 | MMP0642 | MMP0643 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Conserved hypothetical protein. | 0.580 |
| MMP0642 | MMP0716 | MMP0642 | MMP0716 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Acetohydroxyacid synthase small subunit Related. | 0.642 |
| MMP0642 | MMP1346 | MMP0642 | MMP1346 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Basic helix-loop-helix dimerization domain bHLH. | 0.827 |
| MMP0642 | ilvC | MMP0642 | MMP0654 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.429 |
| MMP0642 | rpl7ae | MMP0642 | MMP0641 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | 0.490 |
| MMP0642 | rps28e | MMP0642 | MMP0640 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.419 |
| MMP0642 | uppS | MMP0642 | MMP1345 | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.806 |
| MMP0643 | MMP0642 | MMP0643 | MMP0642 | Conserved hypothetical protein. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.580 |
| MMP0716 | MMP0642 | MMP0716 | MMP0642 | Acetohydroxyacid synthase small subunit Related. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.642 |
| MMP1346 | MMP0642 | MMP1346 | MMP0642 | Basic helix-loop-helix dimerization domain bHLH. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.827 |
| MMP1346 | uppS | MMP1346 | MMP1345 | Basic helix-loop-helix dimerization domain bHLH. | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.964 |
| ilvC | MMP0642 | MMP0654 | MMP0642 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.429 |
| rpl7ae | MMP0642 | MMP0641 | MMP0642 | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.490 |
| rpl7ae | rps28e | MMP0641 | MMP0640 | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | 0.999 |
| rpl7ae | uppS | MMP0641 | MMP1345 | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.530 |
| rps28e | MMP0642 | MMP0640 | MMP0642 | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.419 |
| rps28e | rpl7ae | MMP0640 | MMP0641 | SSU ribosomal protein S28E; Belongs to the eukaryotic ribosomal protein eS28 family. | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | 0.999 |
| uppS | MMP0642 | MMP1345 | MMP0642 | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | Conserved hypothetical archaeal protein; Belongs to the UPF0285 family. | 0.806 |
| uppS | MMP1346 | MMP1345 | MMP1346 | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | Basic helix-loop-helix dimerization domain bHLH. | 0.964 |
| uppS | rpl7ae | MMP1345 | MMP0641 | Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity. | 0.530 |