Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
MMP0644Cation efflux protein. (291 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
    0.979
slpB
S layer protein; Citation: FEMS Microbiol Rev. 1997 Jun;20(1-2):47-98; Extremophiles 6 (5), 351-358 (2002).
   
    0.855
MMP0581
Conserved hypothetical protein.
  
    0.833
tgtA
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
       0.667
MMP1177
Putative iron transport system substrate-binding protein, C-term half.
  
  
 0.665
MMP0646
Hypothetical protein.
  
    0.661
MMP1176
Putative iron transport system substrate-binding protein, N-term half.
  
  
 0.627
trpG
Anthranilate synthase component II; Citation: Knochel T, Ivens A, Hester G, Gonzalez A, Bauerle R, Wilmanns M, Kirschner K, Jansonius JN.(1999). Proc Natl Acad Sci. 96:9479-.
 
  
 0.477
MMP0874
SAM (and some other nucleotide) binding motif.
   
    0.462
trpS
Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp).
  
  
 0.440
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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