STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0656Conserved hypothetical protein. (183 aa)    
Predicted Functional Partners:
MMP1638
MoaA/nifB/pqqE family.
  
    0.777
MMP0655
Hypothetical protein.
  
    0.591
MMP0608
2-hydroxyglutaryl-CoA dehydratase (Component A) related protein; Citation: J Mol Biol 2001 Mar 16;307(1):297-308, Appl Microbiol Biotechnol. 2001 Oct;57(3):263-73.
  
    0.584
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
    0.497
MMP0154
Conserved hypothetical archaeal protein; Belongs to the UPF0288 family.
  
    0.432
MMP0312
Conserved hypothetical archaeal protein.
  
    0.432
MMP0337
Conserved hypothetical protein.
  
    0.432
atwA
Methyl coenzyme M reductase, component A2; Citation: J. Bact. 1993 175: 3196-3203.
  
    0.430
MMP1494
Unnamed protein product.
       0.418
MMP0421
Conserved hypothetical protein.
       0.408
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.