Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP06722-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)    
Predicted Functional Partners:
MMP0398
Conserved hypothetical archaeal protein.
  
 
 0.966
serA
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.700
MMP0334
rRNA methyltransferase related protein.
     
 0.696
MMP1548
Fe-S type hydro-lyases tartrate/fumarate beta region.
  
    0.690
MMP0069
Methyltransferase; Citation: Mol. Gen. Genet. (1998) 258: 69-77.
       0.689
MMP0339
NUDIX hydrolase; Citation: J. Bio. Chem. (1998) 273: 20924-20928.
    0.686
fumA
Fumarate hydratase.
       0.659
MMP1306
Conserved hypothetical protein.
     
 0.642
MMP0670
Conserved hypothetical protein.
  
    0.556
ipa-20r
Conserved hypothetical protein.
       0.538
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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