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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0678Predicted transcriptional regulator; Helix-turn-helix motif. (336 aa)    
Predicted Functional Partners:
MMP1679
Conserved hypothetical archeal protein; Belongs to the UPF0179 family.
  
    0.669
MMP1595
Archaeosine synthase alpha-subunit; ATP/GTP-binding site motif A (P-loop):PUA domain:Queuine/other tRNA-ribosyltransferase:Uncharacterized domain 2.
  
    0.626
MMP1646
Conserved hypothetical archaeal protein.
  
     0.621
recJ
Single stranded DNA-specific exonuclease; Citation: J. Bacteriol. 182 (3), 607-612 (2000).
  
    0.608
mptD
Conserved hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.603
carS
Conserved hypothetical archaeal protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
  
     0.597
MMP1014
Elp3 domain-containing protein; Unnamed protein product.
  
     0.596
MMP0677
Conserved hypothetical protein.
  
    0.589
MMP0547
RecJ related protein; Citation: J. Bact. (2000) 182: 607-612.
  
     0.585
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
    0.573
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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