Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wbpIUDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues. (366 aa)    
Predicted Functional Partners:
wecC
NAD binding site:UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Cannot use NADP instead of NAD; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 
 0.999
MMP1076
Bacterial transferase hexapeptide repeat:ADP-glucose pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP-GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1-P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity); In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 
 0.970
MMP0357
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
 
 
0.911
MMP1091
ADP-glucose pyrophosphorylase.
  
 
 0.880
MMP0353
UDP-glucose/GDP-mannose dehydrogenase Related protein; NAD binding site; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.858
MMP0707
Na+/H+ exchanger.
  
    0.783
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
  
 0.743
glmM
Phosphoglucomutase/phosphomannomutase:Calcium- binding EF-hand; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1- phosphate to glucose-6-phosphate, but at a 5-fold lower rate.
  
  
 0.710
flaB1
Flagellin B1 percursor; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
      
 0.681
flaB2
Flagellin B2; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
      
 0.681
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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