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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP0707Na+/H+ exchanger. (417 aa)    
Predicted Functional Partners:
MMP1068
K+-dependent Na+/Ca+ exchanger related-protein:Sodium/calcium exchanger membrane region.
 
 
 0.923
MMP1581
Putative DNA helicase.
   
 
 0.867
ribK
Conserved hypothetical archaeal protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
    0.811
MMP1642
ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain.
 
 0.783
wecC
NAD binding site:UDP-glucose/GDP-mannose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA). Cannot use NADP instead of NAD; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
    0.779
wbpI
UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues.
  
    0.773
MMP0535
Conserved hypothetical archaeal protein.
      
 0.730
MMP1430
Putative TRK system cation (K+) uptake protein; Citation: J Bacteriol. 1995 Apr;177(7):1908-10; Microbiol. 1998 144:2281-2289.
  
 
 0.725
MMP0704
ParA type ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
 
  
 0.688
MMP1115
Transketolase, N terminal half.
  
  
 0.675
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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