STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iorA2Indolepyruvate oxidoreductase subunit alpha 2; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (578 aa)    
Predicted Functional Partners:
iorB2
Indolepyruvate oxidoreductase subunit beta 2; Citation: Tersteegen, A. 1997. Eur. J. Biochem. 244:862-8.
 
 
 0.993
frdA
Fumarate reductase/succinate dehydrogenase, flavoprotein subunit.
  
 
 0.914
iorB1
Indolepyruvate oxidoreductase subunit beta 1; Citation: Tersteegen, A., et al. 1997. Eur. J. Biochem. 244:862-8.
 
 
 0.857
MMP0716
Acetohydroxyacid synthase small subunit Related.
 
    0.846
MMP0715
Coenzyme F390 synthetase II.
 
  
 0.814
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.675
argH
Argininosuccinate lyase; Citation: R. Cohen Kupiec et. al. FEMS Microbiol Lett. 173, 231-238 (1999).
  
  
 0.674
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.666
aroB
Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
   
  
 0.661
MMP0293
Conserved hypothetical protein.
      
 0.649
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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