Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hcpPrismane; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (546 aa)    
Predicted Functional Partners:
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
  
 
 0.926
nifH-2
NifH/frxC family:ATP/GTP-binding site motif A (P-loop); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
 
 0.918
nifH
Nitrogenase iron protein (nitrogenase component II); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
  
 
 0.918
MMP0723
Conserved hypothetical protein.
  
    0.914
nifD
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
   
 
 0.912
nifK
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
   
 
 0.912
MMP0721
Ferredoxin.
 
    0.795
cobA
uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.
  
  
 0.716
modB-2
Molybdenum transport system permease protein, modB RELATED; Citation: Self, W.T., et al. Res. Microbial. 2001(152): 311-321 Wang, SZ. et al. Biochem and Biophys Res Comm. 1990(169): 1122-1128.
  
  
 0.715
MMP1519
Anion transport system permease protein.
  
  
 0.715
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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