| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP0736 | nadX | MMP0736 | MMP0737 | Conserved hypothetical archaeal protein. | Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.826 |
| MMP1072 | MMP1606 | MMP1072 | MMP1606 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Flavoprotein:DNA/pantothenate metabolism flavoprotein. | 0.901 |
| MMP1072 | argG | MMP1072 | MMP0073 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.932 |
| MMP1072 | asnB | MMP1072 | MMP0918 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | 0.915 |
| MMP1072 | nadX | MMP1072 | MMP0737 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.806 |
| MMP1072 | purA | MMP1072 | MMP1432 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.924 |
| MMP1072 | pyrB | MMP1072 | MMP1659 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7. | 0.913 |
| MMP1072 | pyrI | MMP1072 | MMP1104 | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.911 |
| MMP1606 | MMP1072 | MMP1606 | MMP1072 | Flavoprotein:DNA/pantothenate metabolism flavoprotein. | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | 0.901 |
| MMP1606 | nadX | MMP1606 | MMP0737 | Flavoprotein:DNA/pantothenate metabolism flavoprotein. | Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.793 |
| argG | MMP1072 | MMP0073 | MMP1072 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | 0.932 |
| argG | asnB | MMP0073 | MMP0918 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | 0.925 |
| argG | nadX | MMP0073 | MMP0737 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.822 |
| argG | purA | MMP0073 | MMP1432 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.958 |
| argG | pyrB | MMP0073 | MMP1659 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7. | 0.920 |
| argG | pyrI | MMP0073 | MMP1104 | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.911 |
| asnB | MMP1072 | MMP0918 | MMP1072 | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | Aminotransferase (subgroup I) similar to Aromatic Aminotransferase; Ward DE, de Vos WM, van der Oost J (2002) Archaea 1:133-141; Citation: Matsui I, Matsui E, Sakai Y, Kikuchi H, Kawarabayasi Y, Ura H, Kawaguchi S, Kuramitsu S, Harata K. (2000)J Biol Chem 275:4871-9. | 0.915 |
| asnB | argG | MMP0918 | MMP0073 | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | Argininosuccinate synthase; Citation: Hennigan AN, Reeve JN. (1994). Mol Microbiol 11:655-70; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.925 |
| asnB | nadX | MMP0918 | MMP0737 | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | Protein of unknown function DUF108; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.816 |
| asnB | purA | MMP0918 | MMP1432 | Asparagine synthetase (glutamine-hydrolyzing); Citation: Larsen TM, Boehlein SK, Schuster SM, Richards NG, Thoden JB, Holden HM, Rayment I. (1999) Biochemistry 38:16146-57. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.976 |