Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
MMP0738Elongation factor Tu, domain 2. (309 aa)    
Predicted Functional Partners:
aIF2-2
Translation initiation factor aIF-2, subunit alpha; Citation: Proc. Natl. Acad. Sci. USA 1998, 95: 3726-3730.
  
 0.945
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 0.914
rps2
SSU Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 0.911
aIF-2
Translation initiation factor aIF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
   
 0.910
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 0.908
rpsI
SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
  
 0.900
rpl7ae
Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity.
 
 0.898
aIF-1A
Translation initiation factor 1A (aIF-1A); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
 0.894
rps4e
SSU ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 0.892
rpsJ
SSU ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 0.890
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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