Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0803Conserved archaeal protein. (370 aa)    
Predicted Functional Partners:
MMP0802
Iron-containing alcohol dehydrogenase.
  
    0.911
MMP0804
Hypothetical protein.
  
    0.699
MMP0800
Conserved hypothetical Archael protein.
 
  
 0.643
vhcD
Coenzyme F420-non-reducing hydrogenase subunit delta; Selenium independent; Citation: Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.
  
   0.580
vhuD
F420-non-reducing hydrogenase subunit delta; Contains two selenocysteine residues; Citation: Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224; Belongs to the MvhD/VhuD family.
  
   0.580
MMP0805
Predicted protein.
 
  
 0.574
MMP1608
Conserved hypothetical protein.
   
   0.558
MMP0801
Unnamed protein product.
 
    0.546
MMP0208
Conserved hypothetical protein; Contains 4Fe-4S motif.
  
   
0.540
pyrK
2Fe-2S Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:NADH:cytochrome b5 reductase (CBR); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
   0.513
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (10%) [HD]