close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtaAUroporphyrinogen decarboxylase (URO-D). (363 aa)    
Predicted Functional Partners:
MMP0829
Coenzyme B12-binding:Cobalamin-dependent methionine synthase, B12-binding.
  
 0.972
mtaA-2
Uroporphyrinogen decarboxylase (URO-D).
  
 
 
0.940
hemD
Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.931
cobA
uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.
    
 0.925
mtbA
Uroporphyrinogen decarboxylase (URO-D).
 
  
0.898
mtbC
Coenzyme B12-binding:Cobalamin-dependent methionine synthase, B12-binding.
  
 0.880
MMP0832
Conserved Hypothetical Protein.
 
  
 0.878
MMP0833
Conserved hypothetical protein.
 
  
 0.781
MMP0835
Conserved hypothetical protein.
  
  
 0.766
hemC
Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.
 
 
 0.740
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.