Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP0852Conserved hypothetical protein. (159 aa)    
Predicted Functional Partners:
MMP0914
Conserved hypothetical archaeal protein.
  
    0.890
MMP0913
Conserved hypothetical archaeal protein.
   
    0.852
MMP0721
Ferredoxin.
   
    0.838
MMP1475
Hypothetical protein.
   
    0.804
MMP0851
Conserved hypothetical protein.
  
    0.783
MMP0723
Conserved hypothetical protein.
  
  
 0.676
MMP0614
Related to iron-sulfur flavoprotein of Methanosarcina thermophila; Citation: J. Bact. 2001. 183(21): 6225-33.
  
    0.666
tfb
Transcription initiation factor B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
   
  
 0.660
hdrC1
Heterosulfide reductase, subunit C1; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B); Belongs to the HdrC family.
  
    0.650
aIF-5A
Translation initiation factor IF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
     
 0.636
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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