Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nifENitrogenase iron-molybdenum cofactor biosynthesis protein; This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor); Belongs to the NifD/NifK/NifE/NifN family. (480 aa)    
Predicted Functional Partners:
nifH
Nitrogenase iron protein (nitrogenase component II); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
 
 0.999
nifN
Iron-molybdenum cofactor biosynthesis protein, subunit N; Citation: Kessler et al. 1998 J Bacteriol 180:1504-1511.
  
0.999
nifK
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
  
0.998
NifI1
Nitrogen regulatory protein NifI1; Could be involved in the regulation of nitrogen fixation.
 
  
 0.997
nifX
Nitrogen fixation-related protein; Citation: Kessler et al. 1998 J Bacteriol 180:1504-1511; Gosink et al. 1990 J.Bacteriol 172:1441-1447.
 
  
 0.997
nifD
Oxidoreductase, nitrogenase component 1; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
 
  
0.993
nifH-2
NifH/frxC family:ATP/GTP-binding site motif A (P-loop); The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
 
 0.968
nifI2
Nitrogen regulatory protein NifI2; Could be involved in the regulation of nitrogen fixation.
 
  
 0.950
MMP0658
MoaA/nifB/pqqE family.
 
   
 0.744
modA
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Microbiol 2001;152(3-4):311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
  
  
 0.691
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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