Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kamALysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine. Is involved in the biosynthesis pathway of N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the radical SAM superfamily. KamA family. (433 aa)    
Predicted Functional Partners:
yodP
GCN5-related N-acetyltransferase; Catalyzes the acetylation of beta-lysine to N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the acetyltransferase family.
  
 0.998
MMP0739
Asp/Glu racemase:Aspartate racemase.
     
  0.900
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.844
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
  
  
 0.830
dapL
Aminotransferase (subgroup I); Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
  
  
 0.821
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.816
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
     
 0.816
cheR
Chemotaxis protein CheR.
   
   0.778
napA-2
Na+/H+ exchanger.
  
    0.532
MMP0863
CBS domain.
       0.481
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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