Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yodPGCN5-related N-acetyltransferase; Catalyzes the acetylation of beta-lysine to N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the acetyltransferase family. (274 aa)    
Predicted Functional Partners:
kamA
Lysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine. Is involved in the biosynthesis pathway of N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the radical SAM superfamily. KamA family.
  
 0.998
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
   
  
 0.772
dapL
Aminotransferase (subgroup I); Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
   
  
 0.772
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
      
 0.752
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
      
 0.752
MMP1068
K+-dependent Na+/Ca+ exchanger related-protein:Sodium/calcium exchanger membrane region.
   
  
 0.662
MMP0190
Conserved hypothetical protein; Similar to fragment of K+-dependent Na+/Ca+ exchanger protein.
      
 0.632
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
      
 0.534
MMP0863
CBS domain.
       0.476
napA-2
Na+/H+ exchanger.
       0.473
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (14%) [HD]