Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
napA-2Na+/H+ exchanger. (388 aa)    
Predicted Functional Partners:
MMP0863
CBS domain.
  
  
 0.820
MMP0484
Possible sodium/proton antiporter.
  
    0.669
kamA
Lysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine. Is involved in the biosynthesis pathway of N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the radical SAM superfamily. KamA family.
  
    0.532
MMP0520
Cation transport ATPase.
  
 
 0.509
yodP
GCN5-related N-acetyltransferase; Catalyzes the acetylation of beta-lysine to N6-acetyl-beta- lysine, a compatible solute produced by methanogenic archaea that helps cells to cope with salt stress; Belongs to the acetyltransferase family.
       0.473
MMP0710
Cation-transporting ATPase.
  
 
 0.456
MMP0796
Probable sugar efflux transporter.
  
  
 0.443
MMP1173
Conserved membrane protein.
  
    0.440
MMP0707
Na+/H+ exchanger.
   
 
 0.439
potE
Amino acid/ polyamine transporter; Citation: (1993) Protein Sci. 2: 20-30.
 
 
 0.434
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.