| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMP0002 | pstK | MMP0002 | MMP1490 | L-seryl-tRNA selenium transferase related protein. | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | 0.900 |
| MMP0002 | selD | MMP0002 | MMP0904 | L-seryl-tRNA selenium transferase related protein. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.917 |
| MMP0002 | spcS | MMP0002 | MMP0595 | L-seryl-tRNA selenium transferase related protein. | Conserved hypothetical protein; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.980 |
| MMP0002 | trxB | MMP0002 | MMP0959 | L-seryl-tRNA selenium transferase related protein. | Thioredoxin reductase. | 0.581 |
| MMP0899 | MMP0900 | MMP0899 | MMP0900 | ATP/GTP-binding site motif A (P-loop). | Rhodanese-like. | 0.997 |
| MMP0899 | selD | MMP0899 | MMP0904 | ATP/GTP-binding site motif A (P-loop). | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.678 |
| MMP0900 | MMP0899 | MMP0900 | MMP0899 | Rhodanese-like. | ATP/GTP-binding site motif A (P-loop). | 0.997 |
| MMP0900 | selD | MMP0900 | MMP0904 | Rhodanese-like. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.700 |
| MMP1307 | selD | MMP1307 | MMP0904 | Methyltransferase related protein. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.648 |
| hpt | pstK | MMP0145 | MMP1490 | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | 0.511 |
| hpt | selD | MMP0145 | MMP0904 | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.580 |
| hpt | spcS | MMP0145 | MMP0595 | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | Conserved hypothetical protein; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.594 |
| pstK | MMP0002 | MMP1490 | MMP0002 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | L-seryl-tRNA selenium transferase related protein. | 0.900 |
| pstK | hpt | MMP1490 | MMP0145 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | Hypoxanthine (guanine) phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. | 0.511 |
| pstK | selB | MMP1490 | MMP1336 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | Archaeal translation factor specialized for selenocysteine insertion; Citation: J Bacteriol. 2003 Jan;185(1):107-14. | 0.852 |
| pstK | selD | MMP1490 | MMP0904 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.754 |
| pstK | sepS | MMP1490 | MMP0688 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | Phenylalanyl-tRNA synthetase alpha subunit; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). | 0.618 |
| pstK | spcS | MMP1490 | MMP0595 | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | Conserved hypothetical protein; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. | 0.998 |
| selB | pstK | MMP1336 | MMP1490 | Archaeal translation factor specialized for selenocysteine insertion; Citation: J Bacteriol. 2003 Jan;185(1):107-14. | ATP/GTP-binding site motif A (P-loop); Specifically phosphorylates seryl-tRNA(Sec) to O- phosphoseryl-tRNA(Sec), an activated intermediate for selenocysteine biosynthesis. | 0.852 |
| selB | selD | MMP1336 | MMP0904 | Archaeal translation factor specialized for selenocysteine insertion; Citation: J Bacteriol. 2003 Jan;185(1):107-14. | AIR synthase related protein:Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.667 |