STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobY/cofCNucleoside triphosphate: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase; Appears to catalyze the guanylation of both (S)-2-phospholactate and adenosylcobinamide phosphate; Citation: M. G. Thomas and J. C. Escalante-Semerena, J. Bacteriol., 2000, 182, 4227; Nat. Prod. Rep., 2002, 19(2), 133 - 147. (202 aa)    
Predicted Functional Partners:
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.992
MMP0916
Conserved hypothetical protein.
  
    0.983
chiB
Cobalamin biosynthesis protein B; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 
  0.940
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine.
  
    0.895
MMP1076
Bacterial transferase hexapeptide repeat:ADP-glucose pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP-GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1-P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity); In the C-terminal section; belongs to the transferase hexapeptide repeat family.
 
   
0.874
MMP0018
Transcriptional regulator, LysR Family Member.
       0.773
cbiF
Precorrin-4 C11-methyltransferase; Citation: Eur J Biochem 1998 Jun 1; 254(2):341-6.
      
 0.735
MMP0913
Conserved hypothetical archaeal protein.
  
    0.605
MMP0914
Conserved hypothetical archaeal protein.
  
    0.605
MMP0338
Phosphoribosyltransferase related protein; Belongs to the UPF0284 family.
 
    0.586
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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