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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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chiBCobalamin biosynthesis protein B; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa)    
Predicted Functional Partners:
cobQ
Cobyrinic acid a,c-diamide synthase:Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.996
cobY/cofC
Nucleoside triphosphate: 5'-deoxyadenosylcobinamide phosphate nucleotidyltransferase; Appears to catalyze the guanylation of both (S)-2-phospholactate and adenosylcobinamide phosphate; Citation: M. G. Thomas and J. C. Escalante-Semerena, J. Bacteriol., 2000, 182, 4227; Nat. Prod. Rep., 2002, 19(2), 133 - 147.
  
 
  0.963
cobS
Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.914
cbiA-2
Cobyrinic acid a,c-diamide synthase:Cobyrinic acid a,c-diamide synthase CbiA.
  
 0.905
hisC
Histidinol-phosphate aminotransferase; Citation: Conover RK, Doolittle WF. (1990) J Bacteriol 172:3244-9.
 
  
 0.901
MMP1663
Conserved hypothetical protein.
       0.827
cbiC
Precorrin-8X methylmutase CbiC/CobH.
 
  
 0.810
MMP0950
Conserved hypothetical protein.
  
    0.807
MMP0338
Phosphoribosyltransferase related protein; Belongs to the UPF0284 family.
 
  
 0.802
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.784
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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