Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobAuroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family. (239 aa)    
Predicted Functional Partners:
hemD
Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.998
MMP0089
Conserved hypothetical protein.
 
 
 0.996
hemC
Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.
  
 0.992
cbiL
Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.949
mtaA
Uroporphyrinogen decarboxylase (URO-D).
    
 0.920
mtaA-2
Uroporphyrinogen decarboxylase (URO-D).
    
 0.920
hemB
Delta-aminolevulinic acid dehydratase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82; Belongs to the ALAD family.
  
  
 0.910
gtrA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 0.893
hemL
Glutamate-1-semialdehyde aminotransferase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
     
 0.855
MMP1681
Phosphoadenosine phosphosulfate reductase.
 
  
 0.803
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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