cobA protein (Methanococcus maripaludis S2) - STRING interaction network

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cobA

uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family. (239 aa)

Predicted Functional Partners:

hemD

0.998

MMP0089

0.993

hemC

0.989

cbiL

0.954

mtaA

0.925

mtaA-2

0.925

cbiX(s)

0.887

hemB

0.862

cbiO

0.842

hcp

0.826

Your Current Organism:

Methanococcus maripaludis S2

NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MMP0089	cbiL	MMP0089	MMP0319	Conserved hypothetical protein.	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	0.968
MMP0089	cbiO	MMP0089	MMP1484	Conserved hypothetical protein.	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.456
MMP0089	cbiX(s)	MMP0089	MMP0164	Conserved hypothetical protein.	Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.	0.988
MMP0089	cobA	MMP0089	MMP0966	Conserved hypothetical protein.	uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.	0.993
MMP0089	hcp	MMP0089	MMP0720	Conserved hypothetical protein.	Prismane; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.	0.587
MMP0089	hemB	MMP0089	MMP1258	Conserved hypothetical protein.	Delta-aminolevulinic acid dehydratase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82; Belongs to the ALAD family.	0.514
MMP0089	hemC	MMP0089	MMP0872	Conserved hypothetical protein.	Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.	0.730
MMP0089	hemD	MMP0089	MMP0394	Conserved hypothetical protein.	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.891
cbiL	MMP0089	MMP0319	MMP0089	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Conserved hypothetical protein.	0.968
cbiL	cbiO	MMP0319	MMP1484	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	0.642
cbiL	cbiX(s)	MMP0319	MMP0164	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.	0.986
cbiL	cobA	MMP0319	MMP0966	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.	0.954
cbiL	hemB	MMP0319	MMP1258	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Delta-aminolevulinic acid dehydratase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82; Belongs to the ALAD family.	0.512
cbiL	hemC	MMP0319	MMP0872	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.	0.514
cbiL	hemD	MMP0319	MMP0394	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.736
cbiO	MMP0089	MMP1484	MMP0089	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Conserved hypothetical protein.	0.456
cbiO	cbiL	MMP1484	MMP0319	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Precorrin-2 C-20 methyltransferase; Belongs to the precorrin methyltransferase family.	0.642
cbiO	cbiX(s)	MMP1484	MMP0164	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.	0.821
cbiO	cobA	MMP1484	MMP0966	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	uroporphyrin-III C-methyltransferase; Citation: J Bacteriol. 1991 Aug;173(15):4637-45; Belongs to the precorrin methyltransferase family.	0.842
cbiO	hemC	MMP1484	MMP0872	Cobalt transport protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.	Porphobilinogen deaminase; Citation: Microbiology. 2002 Aug;148(Pt 8):2273-82.	0.414

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