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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thyAThymidylate synthase; Citation: Xu et al., Nature Structural. Biol. 6, 750 (1999). (291 aa)    
Predicted Functional Partners:
MMP0988
RNA methyltransferase related protein; Citation: J Mol Microbiol Biotechnol. 2002 Jan;4(1):71-5.
 
    0.830
rsmA
Dimethyladenosine transferase related protein (rRNA methylase); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
    0.813
cdhA
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
     0.812
cdhD
CO dehydrogenase/acetyl-CoA synthase subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
     0.767
MMP1170
Glycosyl transferase, family 2.
  
  
 0.750
MMP0378
Atrazine chlorohydrolase related protein; Citation: J. Bacteriol. 178: 4894-4900 (1996).
   
  
 0.744
MMP0335
Conserved hypothetical protein.
      
 0.732
cdhB
CO dehydrogenase/acetyl-CoA synthase complex subunit beta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
     0.700
cdh
CO dehydrogenase/acetyl-CoA synthase complex subunit gamma; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
 
     0.675
wbpI
UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP- ManNAc), the activated donor of ManNAc residues.
   
  
 0.665
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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