node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroQ | pheA | MMP0578 | MMP1528 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Prephenate dehydratase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | 0.987 |
aroQ | trpA | MMP0578 | MMP1002 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.710 |
aroQ | trpB | MMP0578 | MMP1003 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.710 |
aroQ | trpC | MMP0578 | MMP1008 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Indole-3-glycerol phosphate synthase; Citation: Knochel T, Pappenberger A, Jansonius JN, Kirschner K. (2002). J Biol Chem. 277:8626-34. | 0.883 |
aroQ | trpD | MMP0578 | MMP1007 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.721 |
aroQ | trpE | MMP0578 | MMP1006 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.970 |
aroQ | trpF | MMP0578 | MMP1004 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | N-(5'phosphoribosyl)anthranilate isomerase; Citation: Sterner R, Kleemann GR, Szadkowski H, Lustig A, Hennig M, Kirschner K. (1996). Protein Sci. 5:2000-8; Belongs to the TrpF family. | 0.671 |
aroQ | trpG | MMP0578 | MMP1005 | Chorismate mutase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | Anthranilate synthase component II; Citation: Knochel T, Ivens A, Hester G, Gonzalez A, Bauerle R, Wilmanns M, Kirschner K, Jansonius JN.(1999). Proc Natl Acad Sci. 96:9479-. | 0.970 |
hisA | pheA | MMP0417 | MMP1528 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Prephenate dehydratase; Citation: MacBeath G, Kast P, Hilvert D. (1998). Biochemistry 37:10062-73. | 0.625 |
hisA | trpA | MMP0417 | MMP1002 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.888 |
hisA | trpB | MMP0417 | MMP1003 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.721 |
hisA | trpC | MMP0417 | MMP1008 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Indole-3-glycerol phosphate synthase; Citation: Knochel T, Pappenberger A, Jansonius JN, Kirschner K. (2002). J Biol Chem. 277:8626-34. | 0.896 |
hisA | trpD | MMP0417 | MMP1007 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.721 |
hisA | trpE | MMP0417 | MMP1006 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.561 |
hisA | trpF | MMP0417 | MMP1004 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | N-(5'phosphoribosyl)anthranilate isomerase; Citation: Sterner R, Kleemann GR, Szadkowski H, Lustig A, Hennig M, Kirschner K. (1996). Protein Sci. 5:2000-8; Belongs to the TrpF family. | 0.848 |
hisA | trpG | MMP0417 | MMP1005 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Citation: Pfeiffer M, Bestgen H, Burger A, Klein A. (1998). Arch Microbiol 170:418-26. | Anthranilate synthase component II; Citation: Knochel T, Ivens A, Hester G, Gonzalez A, Bauerle R, Wilmanns M, Kirschner K, Jansonius JN.(1999). Proc Natl Acad Sci. 96:9479-. | 0.444 |
moaC | trpA | MMP1066 | MMP1002 | Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.546 |
moaC | trpB | MMP1066 | MMP1003 | Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.433 |
moaC | trpC | MMP1066 | MMP1008 | Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Indole-3-glycerol phosphate synthase; Citation: Knochel T, Pappenberger A, Jansonius JN, Kirschner K. (2002). J Biol Chem. 277:8626-34. | 0.899 |
moaC | trpD | MMP1066 | MMP1007 | Molybdopterin cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.710 |