Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1023Transcriptional regulator, TetR Family Member. (200 aa)    
Predicted Functional Partners:
MMP1275
Hypothetical protein.
 
  
 0.766
MMP0719
Predicted transcriptional regluator.
     
 0.661
MMP0629
Conserved hypothetical archaeal protein.
      
 0.632
cdhD
CO dehydrogenase/acetyl-CoA synthase subunit delta; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
      
 0.631
cdh-2
CO dehydrogenase beta subunit/acetyl-CoA synthase subunit epsilon; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation. Belongs to the CdhB family.
      
 0.630
MMP1100
Putative transricptional regulator.
      
 0.630
MMP1022
Conserved hypothetical protein.
  
    0.628
MMP1021
Conserved hypothetical protein.
  
    0.602
MMP0700
Transcriptional regulator PadR-like family; Citation: J. Bacteriol. 2000 182:6724-6731.
 
  
 0.559
MMP1024
MCM family related protein; Citation: Nucleic Acids Res. 1992;20(21):5571-7. Molec. Microbiol. 1998; 29: 955-961. J. Biol. Chem. (2000) 275: 15049-15059; Belongs to the MCM family.
  
    0.553
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (8%) [HD]