Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1036Band 7 protein:Stomatin. (268 aa)    
Predicted Functional Partners:
MMP1035
NfeD domain-containing protein; Unnamed protein product.
 
 
 0.989
MMP1642
ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain.
  
 0.870
MMP0520
Cation transport ATPase.
   
 0.734
MMP0710
Cation-transporting ATPase.
   
 0.734
lon
ATP-dependent Lon protease; Eukaryotic thiol (cysteine) protease, active site:ATP/GTP-binding site motif A (P-loop):Sigma-54 factor interaction domain:Pu..; Belongs to the peptidase S16 family.
  
 
 0.704
MMP1274
acetyl-CoA synthetase, AMP-forming-related; Citation: J Bact 173:6383.
  
  
 0.692
MMP0281
Hypothetical nucleotide binding protein; Citation: Mol. Gen. Genet. 204 (1), 133-140 (1986).
      
 0.688
psmR
Proteasome-activating nucleotidase (PAN); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes A [...]
  
 
 0.686
MMP0963
Aquaporin related.
   
 
 0.630
tmk
Thymidylate kinase.
  
  
 0.622
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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