Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1048Conserved hypothetical protein; Belongs to the UPF0216 family. (129 aa)    
Predicted Functional Partners:
MMP1049
Related to ehbB of Methanothermobacter thermautotrophicus; Citation: Tersteegen, A. and R. Hedderich. 1999. Eur. J. Biochem. 264:930-43.
       0.891
atpD
A1A0 ATPase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
    0.810
MMP1170
Glycosyl transferase, family 2.
       0.803
atpB
A1A0 ATPase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
  
    0.693
MMP1047
Conserved hypothetical protein.
  
    0.670
atpF
A1A0 ATPase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.647
atpE
A1A0 ATPase, subunit IE; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
    0.633
trm1
N2;N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.616
MMP0596
RNA 2'-O-methyl modification protein (NOP5/NOP56); Citation: Hickey, A.J., Macario, A.J.L., and Conway de Macario, E. Gene 253:77-85,2000.
       0.616
flpA-2
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.616
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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