Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1050Conserved hypothetical protein. (215 aa)    
Predicted Functional Partners:
tgtA
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
   
   0.794
MMP0556
Conserved hypothetical protein.
       0.689
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
    0.626
MMP1314
Phosphoesterase, RecJ-like:RNA binding S1:OB-fold nucleic acid binding domain Related protein.
  
    0.604
MMP1472
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
    0.579
MMP1570
TatD-related protein; Citation: Journal Biological Chemistry 2000 275: 16717-16722 Proteins 1997 28: 72-82.
 
     0.547
MMP0281
Hypothetical nucleotide binding protein; Citation: Mol. Gen. Genet. 204 (1), 133-140 (1986).
  
     0.540
HMmB
Archaeal histone B; Citation: Trends in Genetics (2002) 18: 621-626, PNAS (1994) 91: 12624-12628.
  
    0.493
MMP0296
Conserved hypothetical archaeal protein.
  
     0.462
dut
dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003.
 
     0.461
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.