Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1078Conserved Hypothetical Archael Protein. (314 aa)    
Predicted Functional Partners:
MMP0238
Conserved hypothetical archaeal protein.
       0.827
MMP1079
Glycosyl transferase, family 2.
  
  
 0.803
MMP1710
Conserved hypothetical archeal protein.
   
 
 0.721
tgtA
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
    0.667
DP1
DNA polymerase, archaeal type II, small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
    
 
 0.610
glmM
Phosphoglucomutase/phosphomannomutase:Calcium- binding EF-hand; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. Also catalyzes the isomerization of glucose-1- phosphate to glucose-6-phosphate, but at a 5-fold lower rate.
  
  
 0.592
MMP1076
Bacterial transferase hexapeptide repeat:ADP-glucose pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP-GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1-P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity); In the C-terminal section; belongs to the transferase hexapeptide repeat family.
     
 0.573
dut
dUTP diphosphatase; Citation: J. Biol. Chem., Vol. 278, Issue 13, 11100-11106, March 28, 2003.
       0.559
MMP1080
Glycosyl transferase, group 1.
  
  
 0.547
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.510
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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