STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinate-CoA ligase (ADP-forming), beta chain. (362 aa)    
Predicted Functional Partners:
sucD
succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
frdA
Fumarate reductase/succinate dehydrogenase, flavoprotein subunit.
 0.996
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.959
korG
2-oxoglutarate oxidoreductase gamma subunit; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
 
 
 0.959
MMP1067
Uncharacterized iron-sulfur protein MMP1067; Succinate dehydrogenase/fumarate reductase iron-sulfur subunit // Methanosarcina type heterodisulfide reductase subunit D; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 
 0.955
korA
2-oxoglutarate oxidoreductase alpha subunit; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
 0.954
korB
2-oxoglutarate oxidoreductase beta subunit; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
 0.954
korD
2-oxoglutarate ferredoxin oxidoreductase, delta (ferredoxin) subunit; Citation: Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
  0.942
MMP0305
Oxidoreductase family member subunit beta; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
 0.930
MMP0306
Oxidoreductase family member subunit alpha; Citation: Zhang, Z. et al. 1996. J. Biochem. 120:587-99. Tersteegen, A. et al. 1997. Eur. J. Biochem. 244:862-8.
  
 
 0.929
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.