Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1130Conserved hypothetical protein. (132 aa)    
Predicted Functional Partners:
MMP0911
Related to iron-sulfur flavoprotein of Methanosarcina thermophila; Citation: J. Bact. 2001. 183(21): 6225-33.
       0.808
prf1
Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
  
 0.706
MMP0149
Conserved hypothetical protein.
       0.671
adkA
Adenylate kinase; Ferber DM, Haney PJ, Berk H, Lynn D, Konisky J. (1997) Gene 185:239-44; Citation: Rusnak P, Haney P, Konisky J. (1995) J Bacteriol 177:2977-81.
       0.619
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
       0.549
ppiB-2
Peptidyl-prolyl cis-trans isomerase, cyclophilin type.
       0.526
ppiB
Peptidyl-prolyl cis-trans isomerase, cyclophilin type.
  
    0.496
endA
tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
    0.439
comC
L-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase; Citation: J. Bacteriol. 182:3688-3692(2000).
  
    0.433
pyrB
Aspartate carbamoyltransferase; Citation: J. Biol Chem 2000 May 26; 275 (21) 15820-7.
       0.432
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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