Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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comCL-sulfolactate dehydrogenase/(S)-hydroxyglutaric acid dehydrogenase; Citation: J. Bacteriol. 182:3688-3692(2000). (347 aa)    
Predicted Functional Partners:
comE
Sulfopyruvate decarboxylase subunit beta; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.
    
 0.991
comB
2-phosphosulfolactate phosphatase; Citation: Eur. J. Biochem. 268:5176-5188(2001).
  
 
 0.988
comD
Sulfopyruvate decarboxylase subunit alpha; Involved in the biosynthesis of the coenzyme M (2- mercaptoethanesulfonic acid). Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde; Belongs to the ComD family.
    
 0.950
endA
tRNA-intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
  
    0.947
mdh
Malate dehydrogenase, MDHII (NADP+-dependent); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.925
purM-2
AIR synthase related protein:Phosphoribosylformylglycinamidine cyclo-ligase.
       0.616
prf1
Peptide chain release factor aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
  
    0.525
MMP1134
Type A flavoprotein; Citation: Eur. J. Biochem. 1998; 254: 325-332.
       0.499
dapE
Succinyl-diaminopimelate desuccinylase.
 
  
 0.463
cofG
FO synthase, subunit CofG; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
  
  
 0.450
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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