Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP1148Small nuclear ribonucleoprotein (Sm protein). (72 aa)    
Predicted Functional Partners:
RPL37A
Ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
  
 0.997
aEF-2
Translation elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF- [...]
  
 0.974
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.968
hel308
Superfamily II helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
  
 0.950
rpl7ae
Ribosomal protein L7AE:Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs (By similarity). Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, this subunit dramatically stimulates RNase P activity.
  
 0.947
rpmC
LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family.
  
    0.941
aIF-5A
Translation initiation factor IF-5a; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
    0.936
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
  0.935
MMP0157
Conserved hypothetical protein; DNA-binding TFAR19-related protein; Belongs to the PDCD5 family.
   
    0.926
rpoH
RNA polymerase H/23 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
  
 0.924
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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