Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1174Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (217 aa)    
Predicted Functional Partners:
MMP0203
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
  
 0.954
MMP1388
Redox-active disulfide protein 2; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
  
 0.954
trxB
Thioredoxin reductase.
  
 
 0.933
MMP1159
Ferritin.
  
  
 0.911
MMP1635
Thioredoxin:Glutaredoxin:Thioredoxins/glutaredox in.
  
 0.891
MMP0958
Conserved hypothetical protein.
  
 0.871
rbo
Desulfoferrodoxin, ferrous iron-binding site.
  
  
 0.871
MMP1160
Conserved hypothetical protein.
  
  
 0.844
MMP0559
Family of unknown function ThiJ/PfpI.
  
 
 0.826
hsp60
Chaperonin GroEL (thermosome, HSP60 family); Belongs to the TCP-1 chaperonin family.
  
 0.812
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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