Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MMP1180Conserved hypothetical protein. (585 aa)    
Predicted Functional Partners:
MMP1179
SAM (and some other nucleotide) binding motif:Generic methyltransferase.
 
    0.993
MMP1181
Iron transport system binding protein.
  
    0.917
MoeA
Molybdopterin biosynthesis moeA protein; Citation: Xiang,S. et al. Structure (Camb) 2001 Apr 4;9(4):299-310.
  
  
 0.734
MMP0546
Protein of unknown function DUF51.
 
     0.691
MMP0197
ABC-type iron(III) transport system, permease component.
     
 0.649
MMP0802
Iron-containing alcohol dehydrogenase.
  
  
 0.577
MMP1387
Protein of unknown function DUF52; Belongs to the MEMO1 family.
 
     0.574
modA-3
Molybdenum ABC transporter, periplasmic molybdenum-binding protein; Citation: Self WT, et al. Res Mcirobial 2001;152(3-4): 311-21 Reck S, et al. JBC 1996;271(5): 2557-62.
  
  
 0.499
nrdD
Anaerobic Ribonucleoside-triphosphate reductase; Eliasson R, Fontecave M, Jornvall H, Krook M, Pontis E, Reichard P. (1990)Proc Natl Acad Sci U S A 87:3314-8; Citation: Science 273 (5278); 1058-1073 (1996).
 
  
 0.483
MMP0198
ABC-type iron(III) transport system, ATP binding protein.
     
 0.481
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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