Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP1192Conserved hypothetical protein. (371 aa)    
Predicted Functional Partners:
MMP1109
Conserved hypothetical protein.
 
    0.855
cbiD
Cobalamin (vitamin B12) biosynthesis CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.827
rnp2
Ribonuclease P-related protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
  
    0.736
uppS
Undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
       0.689
lysS
Lysyl-tRNA synthetase.
       0.688
MMP1028
NFACT-R_1 domain-containing protein; Unnamed protein product.
       0.661
MMP0169
Conserved hypothetical protein.
       0.616
MMP1210
HTH cro/C1-type domain-containing protein; Unnamed protein product.
  
     0.615
MMP1071
Conserved hypothetical archaeal protein; Belongs to the UPF0201 family.
  
     0.575
MMP0589
Conserved hypothetical protein.
 
    0.563
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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