Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1230DNA polymerase, beta-like region. (352 aa)    
Predicted Functional Partners:
MMP1231
Putative HAD family hydrolase, a fragment.
  
    0.848
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
       0.801
MMP0213
Triphosphoribosyl-dephospho-CoA synthetase related protein.
 
     0.722
MMP0186
Conserved hypothetical protein; SUA5/yciO/yrdC N-terminal:Sua5/YciO/YrdC/YwlC protein family.
       0.636
fwdA
Tungsten containing formylmethanofuran dehydrogenase, subunit A; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162.
 
  
 0.618
MMP1229
Conserved hypothetical protein.
  
    0.616
MMP0564
Conserved hypothetical archaeal protein.
 
    0.615
MMP1580
Dihydropteroate synthase, DHPS:Dihydropteroate synthase-related protein synthase-related protein.
 
    0.612
MMP1399
Aspartate/glutamate/uridylate kinase.
  
    0.588
mch
N5,N10-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
    0.575
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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