Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MMP1243Conserved hypothetical archaeal protein. (217 aa)    
Predicted Functional Partners:
MMP0935
Conserved hypothetical protein; Belongs to the UPF0254 family.
     
 0.721
MMP1498
Conserved hypothetical protein.
     
 0.721
MMP1497
Conserved hypothetical protein.
     
 0.685
bioB
Biotin synthetase.
     
 0.676
MMP1304
Response regulator receiver.
      
 0.633
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.626
MMP0053
Protein of unknown function DUF34.
       0.618
fwdH
Tungsten containing formylmethanofuran dehydrogenase, subunit H; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162.
       0.529
fwdF
Tungsten containing formylmethanofuran dehydrogenase, subunit F; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162.
       0.484
fwdG
Tungsten containing formylmethanofuran dehydrogenase, subunit G; Citation: FEBS Lett. 1989 253: 226-30; Eur. J. Biocehem. 199642: 156-162.
       0.447
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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