Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP1251Conserved Hypothetical Protein with 2 CBS domains. (186 aa)    
Predicted Functional Partners:
MMP1252
CBS domain.
 
    0.997
MMP1016
Conserved Hypothetical protein with 4 CBS domains.
 
    0.938
MMP1332
NAD binding site:FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.740
MMP1250
6-pyruvoyl tetrahydropterin synthase.
  
    0.736
MMP1642
ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain.
  
 0.734
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 
 
 0.707
rpl21e
Ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
   0.700
rps2
SSU Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.699
rps8e
SSU ribosomal protein S8E.
 
 
   0.696
rpl3
LSU Ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.694
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (16%) [HD]