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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP1253Protein of unknown function DUF89. (299 aa)    
Predicted Functional Partners:
purM-2
AIR synthase related protein:Phosphoribosylformylglycinamidine cyclo-ligase.
  
    0.848
MMP1330
Hydrogenase expression/formation protein (HUPF/HYPC).
 
     0.551
pheT
Phenylalanyl-tRNA synthetase beta subunit.
  
    0.531
MMP1252
CBS domain.
       0.519
MMP0735
N-6 Adenine-specific DNA methylase:N6 adenine-specific DNA methyltransferase, D12 class.
     
 0.509
MMP1251
Conserved Hypothetical Protein with 2 CBS domains.
       0.478
MMP0450
Ferredoxin.
 
     0.460
MMP0449
Ferredoxin.
 
     0.432
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.408
MMP1489
Inositol monophosphate related protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively. Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP (By similarity); In the N-terminal section; belongs to the inositol monophosphatase superfamily.
       0.408
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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