Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1259NAD(P)H: rubredoxin oxidoreductase (NPOR). (442 aa)    
Predicted Functional Partners:
MMP0078
Conserved hypothetical protein.
  
 0.939
MMP1135
Flavodoxin:Beta-lactamase-like.
 
  
 0.927
MMP1134
Type A flavoprotein; Citation: Eur. J. Biochem. 1998; 254: 325-332.
 
  
 0.924
MMP1162
Flavodoxin:Beta-lactamase-like.
    
 0.922
fdhA
Formate dehydrogenase alpha subunit; Contains selenocysteine; Citation: J. Bacteriol. 185:2548.
    
 0.918
fdhA-2
Formate dehydrogenase alpha subunit; Contains selenocysteine; Citation: J. Bacteriol 185:2548.
    
 0.918
MMP1332
NAD binding site:FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.829
rtcA
RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
   
 0.750
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.748
rps2
SSU Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.720
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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