Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMP1288Unnamed protein product. (425 aa)    
Predicted Functional Partners:
ubiX
Flavoprotein:Phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
 
 0.997
MMP1645
Amino acid kinase related protein; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
  
 
  0.914
MMP1287
Protein of unknown function UPF0058.
  
    0.773
MMP1663
Conserved hypothetical protein.
 
     0.763
MMP0902
Protein of unknown function DUF126; Belongs to the UPF0107 family.
 
     0.752
pyrK
2Fe-2S Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:NADH:cytochrome b5 reductase (CBR); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
  
 0.698
dnaG
Possible DnaG-type primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
    0.635
MMP0047
Conserved hypothetical protein.
       0.633
MMP0174
HD phosphohydrolase family member; Citation: L. Aravind and E.V. Koonin, Trends Biochem. Sci. 23, 469 (1998).
       0.628
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.623
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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