Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdhB-2Formate dehydrogenase beta subunit. (387 aa)    
Predicted Functional Partners:
fdhA-2
Formate dehydrogenase alpha subunit; Contains selenocysteine; Citation: J. Bacteriol 185:2548.
  
 0.999
fdhA
Formate dehydrogenase alpha subunit; Contains selenocysteine; Citation: J. Bacteriol. 185:2548.
  
 0.993
fdhC
Formate transporter.
  
  
 0.986
MMP1299
Carbonic anhydrase.
  
  
 0.972
hdrA-2
Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 
 0.966
hdrA
Heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 
 0.958
MMP1300
Hypothetical protein.
  
    0.949
fwdD
Tungsten containing formylmethanofuran dehydrogenase, subunit D; Citation: Arch. Microbiol. 1998 170: 389-93; FEBS Lett. 1989 253: 226-30; Eur. J. Biochem. 1996 242: 156-162.
 
 
 0.946
vhuD
F420-non-reducing hydrogenase subunit delta; Contains two selenocysteine residues; Citation: Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224; Belongs to the MvhD/VhuD family.
 
 0.945
vhcD
Coenzyme F420-non-reducing hydrogenase subunit delta; Selenium independent; Citation: Berghofer, Y. et al. 1994. Mol. Gen. Genet. 242:369-373. Halboth,S., Klein,A. (1992) Mol. Gen. Genet. 233:217-224.
 
 
 0.939
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
Server load: low (14%) [HD]