Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhA-2Formate dehydrogenase alpha subunit; Contains selenocysteine; Citation: J. Bacteriol 185:2548. (674 aa)    
Predicted Functional Partners:
fdhB-2
Formate dehydrogenase beta subunit.
  
 0.999
fdhB
Formate dehydrogenase beta subunit.
  
 0.994
fdhC
Formate transporter.
  
  
 0.990
MMP1299
Carbonic anhydrase.
  
    0.969
MMP1300
Hypothetical protein.
  
    0.955
MMP1302
Hypothetical protein.
  
    0.932
porF
Conserved archaeal protein, pyruvate oxidoreductase-associated; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.923
porE
Conserved archaeal protein, pyruvate oxidoreductase-associated; Putative electron transport protein for pyruvate oxidoreductase; Citation: Lin, WC et al, Arch Microbiol 179:444 (2003).
  
 
 0.923
cdhA
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
  
 
 0.921
MMP1259
NAD(P)H: rubredoxin oxidoreductase (NPOR).
    
 0.918
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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