STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP1314Phosphoesterase, RecJ-like:RNA binding S1:OB-fold nucleic acid binding domain Related protein. (761 aa)    
Predicted Functional Partners:
recJ
Single stranded DNA-specific exonuclease; Citation: J. Bacteriol. 182 (3), 607-612 (2000).
  
   
 0.883
fen-1
Flap endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Act [...]
  
  
 0.700
MMP1312
Conserved hypothetical protein.
  
    0.682
MMP0668
Conserved hypothetical protein.
  
    0.671
MMP1284
DEAD/DEAH box helicase:Helicase, C-terminal.
  
     0.666
MMP1554
Conserved hypothetical archaeal protein.
  
    0.664
MMP1311
Ferredoxin.
  
    0.638
MMP1052
Conserved hypothetical archaeal protein.
  
     0.624
aEF-1-2
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
    0.620
MMP1050
Conserved hypothetical protein.
  
    0.586
Your Current Organism:
Methanococcus maripaludis S2
NCBI taxonomy Id: 267377
Other names: M. maripaludis S2, Methanococcus maripaludis LL, Methanococcus maripaludis str. S2, Methanococcus maripaludis strain S2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.